Chronic myelocytic leukemia probably promoted by growth hormone.

Abstract
ISHII, A., KAKUTA, K., TSUCHIYA, S. and KONNO, T. Chronic Myelocytic Leukemia Probably Promoted by Growth Hormone. Tohoku J. Exp. Med., 1989, 158 (3), 263-264-The study shows clinical evidence that growth hormone (GH) presumably promoted Phl-positive chronic myelocytic leukemia in a 14-year-old boy who was receiving GH treatment for growth failure after surgery and irradiation for craniopharyngioma. Leukocytosis associated with immature myelocytic cells and low leukocyte alkaline phosphatase score appeared one year after GH treatment. Cytogenic study showed the presence of Phl chromosome.

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