Trans‐N‐Deoxyribosylase: Substrate Specificity Studies

Abstract
A series of purine bases and analogues were tested as substrates for trans‐N‐deoxyribosylase (EC 2.4.2.6). It was observed that the pyrimidine ring and its substituents on positions 1, 2 and 6, are of minor importance. On the other hand only a few modifications are tolerated on the imidazole moiety, as follows.