Development of Cholinergic Enzymes and Adenosine-triphosphatase Activity of Optic System of Cats in Normal and Restricted Visual Input Conditions

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Abstract
Developmental patterns of acetylcholinesterase (AChE), choline acetyltransferase (CAT) and adenosinetriphosphatase (ATPase) activities were studied in visual centers of normally reared and binocularly deprived cats, from 1 week to 9 months of age. It was found that the activity of these enzymes increased during postnatal development at different rates in various structures. Visual deprivation influenced AChE activity in the lateral geniculate nuclei (LGN) and visual cortex, increasing it by 20 and up to 32%, respectively, but had no effect on the superior colIiculus, visual association cortex and somatosensory cortex. ATPase activity was depressed in the visual cortex of pattern-deprived cats. Visual deprivation had no effect on CAT activity and protein content in the investigated structures.