The use of supports in the lyophilization of oil-in-water emulsions
- 1 June 1968
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 20 (6) , 450-455
- https://doi.org/10.1111/j.2042-7158.1968.tb09780.x
Abstract
The results of drying oil-in-water emulsions by lyophilization have shown this process could be applied to emulsions having dissolved in the aqueous phase a solid material which acts as support for the oily phase after the water has been removed. The rate of creaming and the globule size distribution were also investigated. The tests were made before and immediately after lyophilization, and after 20 and 40 days of storage at room temperature (18–20°) at 0° ±1° and at 40° ±1°. The emulsions were coarser and creaming rate was increased after lyophilization.Keywords
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