Pathophysiology of sepsis: role of nitric oxide and other mediators
- 1 April 1995
- journal article
- research article
- Published by Wolters Kluwer Health in Current Opinion In Anesthesiology
- Vol. 8 (2) , 109-113
- https://doi.org/10.1097/00001503-199504000-00002
Abstract
The multiorgan failure that is the hallmark of severe sepsis results from the activation of a very wide range of mediator cascades, including cytokines, complement, coagulation factors and others. Recently, nitric oxide has emerged as yet another component of this highly complex system. Knowledge of the basic pathophysiological processes involved in sepsis continues to grow, although the clinical applications remain uncertain.Keywords
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