The discovery of a new structural class of potent orally active leukotriene D4 antagonists

This publication has 14 references indexed in Scilit:

• Pharmacology of the leukotriene antagonist verlukast: The (R)-enantiomer of MK-571
  Canadian Journal of Physiology and Pharmacology, 1991
• MK-571, a Potent Antagonist of Leukotriene D₄-induced Bronchoconstriction in the Human
  American Review of Respiratory Disease, 1991
• 677 The therapeutic effects of MK-571, a potent and selective leukotriene (LT) D4 receptor antagonist, in patients with chronic asthma
  Journal of Allergy and Clinical Immunology, 1991
• Inhibition of Exercise-Induced Bronchoconstriction by MK-571, a Potent Leukotriene D₄–Receptor Antagonist
  New England Journal of Medicine, 1990
• Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist
  Journal of Medicinal Chemistry, 1990
• Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D₄ receptor antagonist
  Canadian Journal of Physiology and Pharmacology, 1989
• Asymmetric Dithioacetals III: The Preparation of the Enantiomers of 3-(((3-(2-(7-Chloroquinolin-2-yl)-(E)-ethenyl)ohenyl)-3-dimethylamino-3-oxopropylthio)methyl)thio)propionic Acid (L-660,711) (MK-571), an Antagonist of Leukotriene D4
  HETEROCYCLES, 1989
• Effects of a 5-lipoxygenase inhibitior (L-651,392) on primary and late pulmonary responses to ascaris antigen in the squirrel monkey
  Inflammation Research, 1987
• Inhibition of allergen-induced bronchoconstriction in hyperreactive rats as a model for testing 5-lipoxygenase inhibitors and leukotriene D4 receptor antagonists
  Inflammation Research, 1987
• Characterization of a leukotriene D4 receptor in guinea pig lung.
  Proceedings of the National Academy of Sciences, 1983