Interleukin‐3 Promotes Proliferation and Differentiation of Human Hematopoietic Stem Cells but Reduces Their Repopulation Potential in NOD/SCID Mice
Open Access
- 1 March 2003
- journal article
- research article
- Published by Oxford University Press (OUP) in The International Journal of Cell Cloning
- Vol. 21 (2) , 236-244
- https://doi.org/10.1634/stemcells.21-2-236
Abstract
STEM CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise reviews. STEM CELLS is read and written by clinical and basic scientists whose expertise encompasses the rapidly expanding fields of stem and progenitor cell biology. STEM CELLS welcomes original articles and concise reviews describing basic laboratory investigations of stem cells and the translation of their clinical aspects of characterization and manipulation from the bench to patient care. The journal covers all aspects of stem cells embryonic stem cells/induced pluripotent stem cells; tissue-specific stem cells; stem cell technology: epigenetics, genomics, proteomics, and metabonomics; cancer stem cells; translational and clinical research; and regenerative medicine.Keywords
This publication has 24 references indexed in Scilit:
- The role of blood stem cells in hematopoietic cell renewalThe International Journal of Cell Cloning, 2009
- Interleukin 3 Improves the Ex Vivo Expansion of Primitive Human Cord Blood Progenitor Cells and Maintains the Engraftment Potential of SCID Repopulating CellsThe International Journal of Cell Cloning, 2001
- Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptorJournal of Clinical Investigation, 2000
- Ex VivoCulture of Cord Blood CD34+Cells Expands Progenitor Cell Numbers, Preserves Engraftment Capacity in Nonobese Diabetic/Severe Combined Immunodeficient Mice, and Enhances Retroviral Transduction EfficiencyHuman Gene Therapy, 1999
- Differential Kinetics of Primitive Hematopoietic Cells Assayed In Vitro and In Vivo During Serum‐Free Suspension Culture of CD34 + Blood Progenitor CellsThe International Journal of Cell Cloning, 1999
- Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID miceBone Marrow Transplantation, 1999
- SCID Mouse Models of Human Stem Cell EngraftmentThe International Journal of Cell Cloning, 1998
- Long‐Term Cytokine Production from Engineered Primary Human Stromal Cells Influences Human Hematopoiesis in an In Vivo Xenograft ModelThe International Journal of Cell Cloning, 1997
- Improved engraftment of human hematopoietic cells in severe combined immunodeficient (SCID) mice carrying human cytokine transgenes.The Journal of Experimental Medicine, 1995
- High-Level Multilineage Engraftment of Human Cord Blood Cells in SCI MiceJournal of Hematotherapy, 1993