Distribution of 14C-Phenytoin in Rat Purkinje Cells, Cerebellar and Cerebral Neuronal Tissue after a Single Intraperitoneal Injection
- 1 January 1980
- journal article
- research article
- Published by S. Karger AG in European Neurology
- Vol. 19 (2) , 115-120
- https://doi.org/10.1159/000115135
Abstract
10 adult female littermate rats were injected intraperitoneally with 7.9 µmol (2 mg) of 14C-labeled phenytoin. A perikaryon-enriched Purkinje cell fraction was isolated from the cerebellar specimens. Drug uptake in this fraction was about four times that in other cerebellar neurons and more than twice that in the cerebral neurons.Keywords
This publication has 1 reference indexed in Scilit:
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951