Occurrence and Ecology of Mycoplasma Species (Pleuro-pneumonia-like Organisms) in the Male Urethra

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Abstract
Freundt attempted to isolate mycoplasmata (pleuropneumonia-like organisms) from the urethra in a number of male patients. It was found in 30% of patients with non-gonococcal urethritis, 50% with subclinical NGU (patients with no clinical evidence of urethral infection who presented large numbers of leukocytes on urethral smears), 34% with acute gonorrhea, 48% with epididymitis, but without urethritis, and in 54% of control patients with no genital abnormality. The author concludes that mycoplasmata are apparently common saprophytes of the normal male urethra and that the lower incidence found in patients with clinical NGU and with gonorrhea reflects suppression of the normal microbial flora as a result of inflammation.