Plasma-cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes: the POEMS syndrome. Distinctive radiographic abnormalities.
- 1 July 1981
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 140 (1) , 17-22
- https://doi.org/10.1148/radiology.140.1.7244223
Abstract
Patients [3] with an unusual multisystemic syndrome characterized by polyneuropathy, organomegaly (especially hepatosplenomegaly), endocrine dysfunction, M-protein and skin abnormalities (POEMS syndrome) are discussed. Characteristic radiographic features include single or multiple osteosclerotic lesions and a peculiar variety of bony proliferation. The relationship of the disorder to multiple myeloma and plasmacytoma and the pathogenesis of the skeletal abnormalities remain obscure.This publication has 2 references indexed in Scilit:
- Polyneuropathy and Anasarca: Evidence for a New Connective-Tissue Syndrome and Vasculopathic ContributionAnnals of Internal Medicine, 1976
- Syndrome of Plasma Cell Dyscrasia, Polyneuropathy, and Endocrine DisturbancesAnnals of Internal Medicine, 1974