Trisporic Acid Synthesis in Blakeslea trispora

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Abstract
Cultures of the (-) strain of Blakeslea trispora synthesize trisporic acid C, a sex hormone, from precursors made by cultures of the (+) strain. The precursors are nonacidic compounds isolated from the culture medium of the (+) strain by chloroform extraction. Actidione does not inhibit trisporic acid synthesis from isolated precursors, suggesting that the enzymes involved in the synthesis in cultures of the (-) strain are constitutive.