Studies on the possible role of brain 5-HT systems and adrenocortical activity in behavioural responses to nicotine and diazepam in an elevated X-maze
- 1 January 1986
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 90 (4) , 528-532
- https://doi.org/10.1007/bf00174073
Abstract
Subchronic (6 days) but not acute injections of nicotine (0.4 mg/kg SC) increased spontaneous activity (PPPPPPPr=−0.58; Pr=−0.46; PPP<0.01) hypothalamic 5-HT. The changes in 5-HT and 5-HIAA did not appear to be directly related to the behavioural or adrenocortical responses to either of the drugs.Keywords
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