Case-Control Retrospective Study of Pulmonary Tuberculosis in Heroin-Abusing Patients in China

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Abstract
The objective of this study was to observe the clinical significance of pulmonary tuberculosis in heroin abusers. A case-retrospective study was done to analyze clinical symptoms and severity based on chest X-rays, results of sputum bacterial test and effects of treatment. The clinical symptoms in patients with tuberculosis and heroin addiction were more severe than those in the nonheroin-addicted group. An examination of chest X-rays showed that tuberculosis lesions were involved in two or more lung fields in 80% of the heroin-addicted cases. In 73.3% of the cases, sputum bacterial tests were positive for tuberculosis. After anti-tuberculosis treatment, chest X-rays showed a recovery rate of 46.67%, caves became smaller by 41.7%, and the sputum negative conversion rate was 45.5%. There are significant differences compared with the control group (p < 0.05). The patients with pulmonary tuberculosis combined with heroin addiction had more severe clinical symptoms, more lesion zones found in their chest X-rays, higher sputum tuberculosis positive rates, and poorer treating effects.

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