Macroscopic characterization of cell electroporation in biological tissue based on electrical measurements
- 8 November 2004
- journal article
- research article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 85 (19) , 4520-4522
- https://doi.org/10.1063/1.1818728
Abstract
A method is described to experimentally determine the temporal evolution of state variables involved in the electroporation of biological tissue, i.e., the transmembrane voltage and the macroscopic current flowing in the electropores. Indeed, the electrical parameters of the extracellular, intracellular, and unaltered membrane contributions as well as the electropores electrical characteristics can be deduced from the measurement of the tissue bioimpedance and from the variations of both the macroscopic voltage applied to the tissue and the delivered current.Keywords
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