Successful Treatment of Amegakaryocytic Thrombocytopenic Purpura with Cyclosporine

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Abstract
To the Editor: We would like to report on the successful treatment of amegakaryocytic thrombocytopenic purpura with cyclosporine. The patient was an 80-year-old woman who had been treated with radioiodide in 1979 for Graves' disease. In addition, because of coronary heart disease with cardiac insufficiency and ventricular arrhythmias, she received digoxin, thiazide diuretics, amiloride, propranolol, propafenone, and isosorbide dinitrate. Three weeks before admission (November 1982) she reported melena and hematemesis, as well as petechiae and hemorrhages in the skin. On admission, clinical examination revealed no signs of malignant lymphoma, which was confirmed by roentgenography, computed tomography, ultrasonography, and bone scanning. . . .