Effect of intracerebral hydrocortisone on unit activity of diencephalon and midbrain in cats.

Publisher Website
Google Scholar
Abstract
The effect of hydrocortisone was assessed on spontaneous frequencies of units in the posterior diencephalon and midbrain, the activity of several units at each of 2 or 3 sites being recorded simultaneously. Units of the hypothalamus and zona incerta revealed significant alteration within 10 minutes after intravenous hydrocortisone (25 mg). In contrast, units recorded from these regions revealed a more delayed change following intracerebral injection of hydrocortisone (250 [mu]g) into the contralateral midbrain. The spontaneous firing rates of half of all recorded midbrain units were altered within 10 minutes after intrahypothalamic injection of hydrocortisone (250 [mu]g). The results suggest a greater sensitivity of diencephalic than of midbrain neurons to local hydrocortisone.

This publication has 2 references indexed in Scilit: