Treatment of Relapsing Clostridium difficile Diarrhea with Lactobacillus GG

Publisher Website
Google Scholar
Abstract
Thirty-two patients with relapsing C. difficile diarrhea were treated with a lyophilized preparation of Lactobacillus GG; 23 were outpatients treated in Boston, Massachusetts, and nine were nursing-home patients in Baltimore, Maryland. After receiving Lactobacillus GG, all subjects improved symptomatically. Twenty-seven (84%) patients were cured by the single treatment, based on a minimum follow-up of 2 months. Five others relapsed within 10 days after initial Lactobacillus GG treatment; three were retreated and cured, and two were lost to follow-up and are considered failures. The use of Lactobacillus GG offers a safe and. relatively effective alternative to antibiotic therapy for relapsing C. difficile diarrhea.

This publication has 0 references indexed in Scilit: