LIPOMELANOTIC RETICULAR HYPERPLASIA OF LYMPH NODES
- 1 January 1948
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 81 (1) , 19-36
- https://doi.org/10.1001/archinte.1948.00220190027003
Abstract
THE ASSOCIATION of a peculiar type of hyperplasia of lymph nodes with chronic dermatitis was first pointed out by Pautrier and Woringer1in 1937. They reported 11 cases in which there were dermatitis and lymphadenopathy. In 4 instances lymph nodes were removed and showed a peculiar type of hyperplasia. The dermatitis varied in type and degree but was usually erythematous, desquamative and associated with pruritus. The lymph node hyperplasia was characterized by the multiplication of reticular cells, the presence of intracellular fat and melanin pigment and slight infiltration with eosinophils. In 1941 Soloff2reported a case in which there were similar changes in the inguinal lymph nodes in a patient who died of disseminated miliary tuberculosis. It should be noted that in many of the reported cases there was widespread lymphadenopathy, which led to a clinical diagnosis of lymphoblastoma. In this paper 6 cases of chronic dermatitis, pruritusThis publication has 0 references indexed in Scilit: