Distribution of Glycine, ?-Aminobutyric Acid, Glutamate Decarboxylase, and ?-Aminobutyric Acid Transaminase in Rabbit and Mudpuppy Retinas

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Abstract
The distributions of glycine, GABA, glutamate decarboxylase [GAD] (EC 4.1.1.15), and GABA transaminase (EC 2.6.1.19) were determined in rabbit and mudpuppy retinas. In both species, peak levels of the amino acids and the enzymes occurred in the inner plexiform layer. GAD was almost entirely confined to the inner plexiform layer. Determinations were also made of the GABA content of 107 individual putative amacrine cell somas from mudpuppy retina. Of those somas .apprx. 30% had high endogenous GABA levels.