The effect of sodium and calcium ions on the release of catecholamines from the adrenal medulla: sodium deprivation induces release by exocytosis in the absence of extracellular calcium

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Abstract
1. Perfusing bovine adrenal glands with Na+-free Locke solution for 15-40 min did not modify the increase in the release of catecholamines from glands stimulated by acetylcholine. However, after 80-100 min of perfusion with Na+-free solution, the response to acetylcholine stimulation was decreased or abolished.

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