Complement activation in psoriasis
- 1 January 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical and Experimental Dermatology
- Vol. 15 (1) , 16-20
- https://doi.org/10.1111/j.1365-2230.1990.tb02011.x
Abstract
Plasma from 16 patients with psoriasis and 12 healthy control subjects were measured for iC3b, C4d, and Bb fragments generated by complement activation. Plasma concentrations for iC3b, C4d, and Bb fragments were found to be significantly increased in the patients with psoriasis. The highest concentrations of these complement activation fragments were seen in patients with erythrodermic pustular psoriasis, psoriatic arthritis, and Reiter's syndrome. The serum concentrations of complement components and regulatory proteins were normal or elevated in almost all samples.Keywords
This publication has 18 references indexed in Scilit:
- Properdin Factor B Allotypes in Japanese Patients with PsoriasisThe Journal of Dermatology, 1987
- Psoriasis and Leukocyte Chemotaxis.Journal of Investigative Dermatology, 1987
- Identification of C5ades arg and an Anionic Neutrophil-Activating Peptide (ANAP) in Psoriatic ScalesJournal of Investigative Dermatology, 1986
- HLA-linked complement polymorphisms (C2, BF) in psoriasisArchives of Dermatological Research, 1983
- Patch tests with killed sonicated microflora in patients with psoriasisArchives of Dermatology, 1982
- Microbial factors in psoriasisArchives of Dermatology, 1982
- Immunopathology of Psoriasis: A Comparison with Other Parakeratotic LesionsJournal of Investigative Dermatology, 1982
- Analysis of Immunological Responses in Psoriatic Lesions: (1) Immunopathological Studies on Psoriatic LesionsJournal of Investigative Dermatology, 1980
- Immunopathology of psoriasisArchives of Dermatological Research, 1979
- Autoimmunity in psoriasisArchives of Dermatological Research, 1978