Cancer of the glottis: prognostic factors in radiation therapy.

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Abstract
A multivariate analysis of the prognostic factors was conducted in 96 patients wiht early glottic cancer treated by radiation therapy. Of these, 73 had [stage] T1 and 23 had T2 tumor. The primary tumor was controlled in 82% of T1 and 74% of T2 lesions. Actuarial 5-yr survival rates were 87% for T1 and 74% for T2. Carcinoma of the anterior commissure associated with bilateral vocal cord involvement, subglottic tumor extension, persistent or recurrent laryngeal edema, and impaired cord mobility adversely influenced the prognosis. Irradiation probably is the treatment of choice for glottic cancer limited to the vocal cords or with minimal extension to the anterior commisure or supraglottic larynx.

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