Phage mediated horizontal transfer of thesopE1gene increases enteropathogenicity ofSalmonella entericaserotype Typhimurium for calves
Open Access
- 1 December 2002
- journal article
- Published by Oxford University Press (OUP) in FEMS Microbiology Letters
- Vol. 217 (2) , 243-247
- https://doi.org/10.1111/j.1574-6968.2002.tb11482.x
Abstract
Epidemiological evidence shows that the sopE1 gene is associated with Salmonella Typhimurium phage types causing epidemics in cattle. In this study we demonstrate that horizontal transfer of the sopE1 gene by lysogenic conversion with the SopEΦ increased enteropathogenicity of S. Typhimurium in the bovine ligated ileal loop model. These data support the hypothesis that phage mediated horizontal transfer of the sopE1 gene contributes to the emergence of epidemic cattle-associated S. Typhimurium clones.Keywords
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