The c-erb-A protein is a high-affinity receptor for thyroid hormone
- 1 December 1986
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 324 (6098) , 635-640
- https://doi.org/10.1038/324635a0
Abstract
Hormone binding and localization of the c-erb-A protein suggest that it is a receptor for thyroid hormone, a nuclear protein that binds to DNA and activates transcription. In contrast, the product of the viral oncogene v-erb-A is defective in binding the hormone but is still located in the nucleus.Keywords
This publication has 51 references indexed in Scilit:
- Molecular Cloning of the Chicken Progesterone ReceptorScience, 1986
- The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors.The EMBO Journal, 1986
- v-erbA cooperates with sarcoma oncogenes in leukemic cell transformationCell, 1986
- Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-ANature, 1986
- Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene productNature, 1985
- Sequencing the erb A Gene of Avian Erythroblastosis Virus Reveals a New Type of OncogeneScience, 1984
- Efficient isolation of genes by using antibody probes.Proceedings of the National Academy of Sciences, 1983
- Nucleotide sequence of rous sarcoma virusCell, 1983
- Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenesCell, 1983
- Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virusCell, 1982