Acute Non‐lymphocytic Leukaemia in the Third Trimester of Pregnancy

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Abstract
Summary: A 28‐year‐old woman with acute myeloblastic leukaemia was effectively treated with cytosine arabinoside and 6‐thioguanine during the third trimester of pregnancy and a complete remission achieved. A normal infant was delivered at term. The patient survived for 27 months and the baby is now 2½ years old with normal physical and mental development.The literature on management of acute non‐lymphocytic leukaemia during the second and third trimester of pregnancy is reviewed and it is concluded that effective combination chemotherapy improves fetal survival.

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