Structural view of cadherin-mediated cell-cell adhesion
- 1 March 1999
- journal article
- review article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 55 (3) , 359-367
- https://doi.org/10.1007/s000180050297
Abstract
Following the multiplication of biochemical, biophysical and structural studies describing cadherin molecules and their interactions, several ideas have emerged to explain the mechanisms of cadherin-mediated cell adhesion. Although different models were proposed for cadherin interactions, a consensus has come forth considering lateral dimerization of cadherins as being a central component of the cell-cell adhesion process. This review summarizes the recent development in structural studies of cadherins.Keywords
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