Space Radiation Cancer Risks and Uncertainties for Mars Missions
Top Cited Papers
- 1 November 2001
- journal article
- Published by Radiation Research Society in Radiation Research
- Vol. 156 (5) , 682-688
- https://doi.org/10.1667/0033-7587(2001)156[0682:srcrau]2.0.co;2
Abstract
Cucinotta, F. A., Schimmerling, W., Wilson, J. W., Peterson, L. E., Badhwar, G. D., Saganti, P. B. and Dicello, J. F. Space Radiation Cancer Risks and Uncertainties for Mars Missions. Radiat. Res. 156, 682–688 (2001). Projecting cancer risks from exposure to space radiation is highly uncertain because of the absence of data for humans and because of the limited radiobiology data available for estimating late effects from the high-energy and charge (HZE) ions present in the galactic cosmic rays (GCR). Cancer risk projections involve many biological and physical factors, each of which has a differential range of uncertainty due to the lack of data and knowledge. We discuss an uncertainty assessment within the linear-additivity model using the approach of Monte Carlo sampling from subjective error distributions that represent the lack of knowledge in each factor to quantify the overall uncertainty in risk projections. Calculations are performed using the space radiation environment and transport cod...Keywords
This publication has 33 references indexed in Scilit:
- Neutron RBE for induction of tumors with high lethality in Sprague-Dawley rats.Radiation Research, 2000
- Model for Radial Dependence of Frequency Distributions for Energy Imparted in Nanometer Volumes from HZE ParticlesRadiation Research, 2000
- Monte Carlo mixture model of lifetime cancer incidence risk from radiation exposure on shuttle and international space stationMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1999
- Estimation of risk based on multiple events in radiation carcinogenesis of rat skinAdvances In Space Research, 1994
- Mutation induction by heavy ionsAdvances In Space Research, 1994
- Initial Events in the Cellular Effects of Ionizing Radiations: Clustered Damage in DNAInternational Journal of Radiation Biology, 1994
- Inactivation and Mutation Induction in V79 Cells by Low Energy Protons: Re-evaluation of the Results at the LNL FacilityInternational Journal of Radiation Biology, 1993
- Early and late mammalian responses to heavy charged particlesAdvances In Space Research, 1986
- High-LET Radiation CarcinogenesisRadiation Research, 1985
- Mutation and Inactivation of Cultured Mammalian Cells Exposed to Beams of Accelerated Heavy IonsInternational Journal of Radiation Biology, 1979