TISSUE PRESSURE (INTRACUTANEOUS, SUBCUTANEOUS, AND INTRAMUSCULAR) AS RELATED TO VENOUS PRESSURE, CAPILLARY FILTRATION, AND OTHER FACTORS 12

Open Access
Publisher Website
Google Scholar
Abstract
Tissue pressures were measured directly, chiefly on normal human subjects. Subcut and intracut. pressures in the leg were only slightly elevated by prolonged venoua congestion. Intramuscular pressure, normally 5-10 cm. H2O, in anterior tibial muscles of recumbent subjects, rises at once to 20-35 cm. H2O on stand-ing and continues to rise to 50 cm. H2O during prolonged congestion. Pressure in the loosely covered gastrocnemiua rises only to 20 cm. H2O during congestion. Intramuscular pressure is detned. by filling of the vessels, presence of extravascular fluid, tightness of fascial investment, contractile force of the muscle and other factors. Max. voluntary contractions of various muscles elevate intramuscular pressure to values of 10 to 118 cm. H2O. During quiet standing, up to 2.5 hrs. leg vol. continues to increase at rates expected on the assumption that flitration ceases in high pressure muscles but continues indefinitely in skin and gastrocnemius muscle which are low pressure filtering areas.