Abstract
A C3H mouse embryo-derived cell line was consistently 5 to 30-fold more sensitive to the antiviral activity of mouse interferon than 2 other homologous [mouse fibroblast L and embryo fibroblast] cells routinely used in the assay of mouse interferon. [Interferons were assayed by the inhibition of cytopathic effect of vesicular stomatitis virus, encephalomyocarditis virus or Semliki Forest virus in monolayer cultures].