HPLC Analysis of Diuron and Metabolites in Blood and Urine
- 1 July 1990
- journal article
- case report
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 14 (4) , 231-234
- https://doi.org/10.1093/jat/14.4.231
Abstract
A high-pressure liquid chromatographic method for the determination of diuron and its metabolites in human urine and blood is presented. The synthesis of different metabolites and of a suitable internal standard is described and the structure of the compounds is determined by mass spectrometry and nuclear magnetic resonance spectroscopy. The method is applied to an overdose case.Keywords
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