Multidisciplinary treatment for central nervous system tumours with nitrosourea compounds
- 1 December 1978
- journal article
- research article
- Published by Springer Nature in Acta Neurochirurgica
- Vol. 41 (4) , 287-299
- https://doi.org/10.1007/bf01811342
Abstract
The authors report the results of a controlled clinical trial in patients with primitive and metastatic CNS tumours treated with combined therapy: surgery, radiotherapy, and chemotherapy (BCNU or CCNU). A total of 102 patients were treated, 50 with BCNU, and 52 with CCNU. The overall response (R. + P.R.) was 68% for the BCNU group, and 65% for the CCNU group. No significant differences were found between the two types of treatment, either in terms of response or in terms of quality and length of survival.Keywords
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