HLA Antigens in Patients with and without a Family History of Schizophrenia
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 34 (5) , 291-296
- https://doi.org/10.1159/000153482
Abstract
Frequencies of HLA antigens (A, B, C and DR) were studied in patients with (n = 49) and without (n = 67) a family history of schizophrenia and in controls. Among the patients with a family history of schizophrenia significant increases were found in the A3 and B5 antigens while significant decreases were observed for the A1, A11 and B8 antigens. In a material of schizophrenic siblings the sharing of HLA haplotypes was consistent with normal segregation.Keywords
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