Solution Dynamics of Phosphonate Ester Hydrolysis
- 1 February 1993
- journal article
- Published by Taylor & Francis in Phosphorus, Sulfur, and Silicon and the Related Elements
- Vol. 75 (1-4) , 131-134
- https://doi.org/10.1080/10426509308037382
Abstract
The character of buffer-catalyzed hydrolysis of four phosphonates, bis-(4-nitrophenyl) methylphosphonate (NMN), 4-nitrophenyl 2-propyl methylphosphonate (IMN), 2-(3,3-dimethyl)butyl methylphosphonofluoridate (soman), and 4-nitrophenyl4-methylphenacyl methylphosphonate (MPMN), was investigated. The latter hydrolyzes by an intramolecular nucleophilic mechanism. The transition state for each reaction is discussed.Keywords
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