Plasmodium Falciparum-Infected Anopheles Stephensi Inconsistently Transmit Malaria to Humans
- 1 November 1990
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 43 (5) , 441-445
- https://doi.org/10.4269/ajtmh.1990.43.441
Abstract
Malaria was transmitted to only 5 of 10 volunteers bitten by 1–2 Anopheles stephensi carrying sporozoites of the 3D7 clone of the NF54 strain of Plasmodium falciparum in their salivary glands. Parasites were detectable by culture in blood taken 7–10 days following exposure and by thick blood film 14–16.5 days after exposure. Infectivity did not correlate with the numbers of sporozoites in the salivary glands.This publication has 8 references indexed in Scilit:
- Evidence for a 6.5-day minimum exoerythrocytic cycle for Plasmodium falciparum in humans and confirmation that immunization with a synthetic peptide representative of a region of the circumsporozoite protein retards infectionJournal of Clinical Microbiology, 1989
- Estimate of Plasmodium Falciparum Sporozoite Content of Anopheles Stephensi used to Challenge Human VolunteersThe American Journal of Tropical Medicine and Hygiene, 1989
- RAPID DIAGNOSIS OF MALARIA BY ACRIDINE ORANGE STAINING OF CENTRIFUGED PARASITESThe Lancet, 1989
- A MODEL FOR PLASMODIUM-FALCIPARUM SPOROZOITE CHALLENGE AND VERY EARLY THERAPY OF PARASITEMIA FOR EFFICACY STUDIES OF SPOROZOITE VACCINES1988
- Genetic Analysis of the Human Malaria Parasite Plasmodium falciparumScience, 1987
- SAFETY AND EFFICACY OF A RECOMBINANT DNA PLASMODIUM FALCIPARUM SPOROZOITE VACCINEThe Lancet, 1987
- Efficacy of Murine Malaria Sporozoite Vaccines: Implications for Human Vaccine DevelopmentScience, 1987
- Malaria Transmitted to Humans by Mosquitoes Infected from Cultured Plasmodium falciparumThe American Journal of Tropical Medicine and Hygiene, 1986