AN EASY-TO-USE MAXIMUM-LIKELIHOOD METHOD OF ESTIMATING THE ASCERTAINMENT PROBABILITY

  • 1 January 1981
    • journal article
    • research article
    • Vol. 33  (5) , 785-801
Abstract
An easy-to-compute statistic for estimating the ascertainment probability [in familial genetics] is proposed. This statistic is determined through the use of the maximum-likelihood principle and in addition to being easy to compute, has the properties of a maximum-likelihood statistic. Variance tables are given to facilitate computation of the estimate and its variance.