Calciferol and its relatives. Part 20. A synthesis of Windaus and Grundmann's C19 ketone
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 23,p. 2608-2612
- https://doi.org/10.1039/p19770002608
Abstract
Starting from 1β-[(R)-2- hydroxy-1-methylethyl]-7aβ-methyl-3aα,6,7,7aβ-tetrahydroindane (1) syntheses have been effected of two bicyclic compounds suitable as intermediates for conversion into vitamin D-active products, viz. Windaus and Grundmann's ketone (20){7aβ-methyl-1β-[(1R,4R)-1,4,5-trimethylhex-trans-2-enyl]-3aα,4,5,6,7,7aβ-hexahydroindan-4-one}, and des-AB-cholestane-8β,25-diol (23){4β-hydroxy-1β-[(R)-5-hydroxy-1,5-dimethylhexyl]-7aβ-methyl-3aα,4,5,6,7,7aβ-hexahydroindane}.This publication has 0 references indexed in Scilit: