Preanaesthetic Medication with Rectal Diazepam in Children

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Abstract
With the purpose of avoiding injections to children, the quality of rectal premedication with a solution of diazepam (Apozepam) was investigated in a double-blind study. Compared with a lytic cocktail (containing pethidine, promethazine and chlorpromazine), adequate preanesthetic sedation was obtained with rectally administered diazepam in a dose of 0.75 mg/kg. Following rectal diazepam, the majority of the children were very restless during recovery, but the combination of diazepam premedication and a small dose of lytic cocktail given i.m. during anesthesia secured a smooth recovery in practically all children. The proportion of cases classified as unsatisfactory was higher in children younger than 5 yr old than in the older children.

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