FIRST RESPONSE OF DEVELOPING OPOSSUM GONADS TO EQUINE GONADOTROPIC TREATMENT1
- 1 January 1943
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 32 (1) , 17-26
- https://doi.org/10.1210/endo-32-1-17
Abstract
Fourteen [male] and 13 [female] pouch-young and juvenile opossums were treated with equine gonado-trophin for varying periods between the 8th and 150th days of life. The condition of the prostate gland in the [male] demonstrates that testes can respond to gonadotrophins by precocious secretion of [male] sex hormones as early as day 70; slight indications suggested a mild response as early as day 63. The condition of the reproductive tract in [female][female] proved that the ovaries could respond to gonadotrophic stimulation by precocious sex-hormone secretion subsequent to day 100. Previous to day 100 the treatments caused precocious conversion of embryonic egg-nests into primordial follicles but did not stimulate hormone secretion in detectable amts. Since it appears justified to believe that gonads incapable of secreting hormones precociously as a result of gonadotrophic stimulation do not normally secrete hormones at such periods, it would follow that the early differentiation of sex ducts and accessory reproductive organs in the opossum could not be controlled by gonadal secreted hormones.This publication has 0 references indexed in Scilit: