An irradiation-reduced hybrid panel for fine-structure mapping of the Xq28 region in the human genome
- 1 January 1993
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 62 (1) , 58-59
- https://doi.org/10.1159/000133447
Abstract
Irradiation-reduced somatic cell hybrids containing fragments of the human X chromosome were constructed. Analysis of 16 hybrids that retained the Xq28 region with 12 Xq28-specific markers identified at least six different breakpoints, supporting the order cen-DXS304-DXS374-(DXS33, DXS134, DXS52, DXS15)-RCP-(DXS254, G6PD, F8C)-(DXS115, DXYS64)-qter. The generated panel of hybrids provides a useful tool for fine mapping of probes in the Xq28 region.Keywords
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