Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling
- 1 August 2016
- Vol. 24 (8) , 1271-1281
- https://doi.org/10.1016/j.str.2016.05.017
Abstract
No abstract availableFunding Information
- National Health and Medical Research Council
- Australian Cancer Research Foundation
- Victorian Government Operational Infrastructure
- Leukaemia Foundation
This publication has 33 references indexed in Scilit:
- The βc receptor family – Structural insights and their functional implicationsCytokine, 2015
- Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer AntibodyCell Reports, 2014
- Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone ReceptorScience, 2014
- The GM–CSF/IL‐3/IL‐5 cytokine receptor family: from ligand recognition to initiation of signalingImmunological Reviews, 2012
- The Structure of the GM-CSF Receptor Complex Reveals a Distinct Mode of Cytokine Receptor ActivationCell, 2008
- Colony-stimulating factors in inflammation and autoimmunityNature Reviews Immunology, 2008
- The IL-3/IL-5/GM-CSF Common β Receptor Plays a Pivotal Role in the Regulation of Th2 Immunity and Allergic Airway InflammationThe Journal of Immunology, 2008
- An improved resolution structure of the human β common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitopeActa Crystallographica Section F Structural Biology and Crystallization Communications, 2006
- Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the ComplexScience, 1992
- Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.Proceedings of the National Academy of Sciences, 1990