Stoichiometry and accessibility of histone 3 sulfhydryl groups in chromatin subunits

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Abstract
The accessibility of the sulfhydryl groups of histone 3 (H3) in chromatin subunit particles has been investigated by reaction with p-hydroxymercuribenzoate. The results indicate that the carboxy-terminal regions of H3 are buried in the native particle, and suggest the presence of 2 mol of H3 per chromatin monomer.