A New Bastadin from the Sponge Psammaplysilla purpurea
- 1 January 1993
- journal article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 56 (1) , 153-157
- https://doi.org/10.1021/np50091a025
Abstract
A new bastadin 2 and the previously reported bastadins 5 [3], 7 [4], and 12 (formerly bastadin 9) [5] were isolated from the Verongid sponge Psammaplysilla purpurea collected in Pohnpei. Compound 2 is mildly cytotoxic against several cell lines and inhibits the enzymes topoisomerase II and dehydrofolate reductase.Keywords
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