Changing values for the normal thyroid radioactive iodine uptake test

17 October 1977

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. 238 (16) , 1741-1743
https://doi.org/10.1001/jama.238.16.1741

Abstract

The normal range for thyroid radioactive iodine (RAI) uptake values in the Minneapolis [USA] area has shifted twice in the past 20 yr. The mean 24-h thyroid RAI uptake value in 29 normal subjects [human] was 20.5% .+-. 6.1%. (SD) in 1975, whereas only 4 yr previously it was found to be 11.5% .+-. 4.4% (SD) in 51 normal subjects. In a previously published study, the mean thyroid RAI uptake value in normal subjects in this area was 25% .+-. 8% (SD) in 1957. The I content of commercially baked white bread currently available in this area was found to average only 26 .mu.g per single slice of bread; the change in the mean 24-h thyroid RAI uptake value that was observed between 1971 and 1975 is most likely due to a marked reduction in this source of dietary I.

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