Medullipin System of Blood Pressure Control

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Abstract
Renomedullary interstitial cells of renal papilla secrete medullipin I, which is conveyed to the liver and converted to medullipin II, a vasodilator that suppresses sympathetic tone, causes diuresis-natriuresis, and has a suppressive effect on the central nervous system. These are opposite effects to those of renin-angiotensin.

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