Failure of Dengue Viruses to Replicate in Culex quinquefasciatus (Diptera: Culicidae)
- 1 November 1992
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Medical Entomology
- Vol. 29 (6) , 911-914
- https://doi.org/10.1093/jmedent/29.6.911
Abstract
Culex quinquefasciatus (Say) and Aedes aegypti (L.) were parenterally infected with dengue viruses and virus replication was monitored at intervals after infection in each species. Dengue viruses replicated rapidly in Ae. aegypti, reaching a peak titer of 106–107 mosquito infectious dose 50 (MID50) per mosquito. In Cx. quinquefasciatus, however, dengue virus replication did not occur. We conclude that this mosquito species is refractory to infection with dengue viruses and, therefore, does not serve as a vector in nature.Keywords
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