Hypertension Treated withRauwolfia canescens
- 4 October 1956
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 255 (14) , 646-650
- https://doi.org/10.1056/nejm195610042551404
Abstract
THE widespread acceptance of the preparations of Rauwolfia serpentina for the treatment of patients with arterial hypertension and mental disorders has stimulated further investigation regarding other forms of Rauwolfia. One of these species, R. canescens, has been reported by Chakravarti1 to show greater adrenolytic activity with less hypnotic effect than R. serpentina. This effect was attributed by Mukherjee2 to a crystalline alkaloid, rauwolscine, which was isolated in 19413 and was thought to be the active principle of R. canescens. Since then the well known alkaloid, reserpine, has been isolated from R. canescens by Klohs and his co-workers.4 In addition, other . . .Keywords
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