Abstract
It is indeed a great honor that the Society has given to me in inviting me to come here to present the 47th Annual Charles Franklin Craig Lecture. I feel greatly indebted, and want to begin by expressing my best thanks to its officers and to the members of the selection committee. It is a unique privilege that not many foreigners have received and that I highly appreciate. It is natural that on this occasion I should speak about malaria, the disease which has occupied most of my professional life, and that I refer particularly to the work carried out in Venezuela, and to its antecedents and development. Malaria was the most deadly endemic and epidemic disease prevalent in this country before 1936, the year in which the activities for its control on a national scale were established under my direction. It covered two-thirds of the territory, 600,000 km.

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