Compliance with treatment regimens for pediatric rheumatic diseases

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Abstract
Children with pediatric rheumatic diseases (PRDsj are required to comply with long-term treatment regimens that may not have immediate beneficial effects or may be required primarily to prevent further morbidity. As with other chronic disease regimens, compliance can be a significant problem that interferes with treatment efficacy and adequate clinical outcomes. This paper reviews (1 j the prevalence and types of compliance problems in the management of PRDs; (2) patient/family, disease, and regimen /actors that may be associated with treatment noncompliance; and (3) strategies for improving compliance with regimens for PRDs.