THE SINGLE BREATH N2-TEST PREDICTS THE RATE OF DECLINE IN FEV1 - THE STUDY OF MEN BORN IN 1913 AND 1923
- 1 July 1986
- journal article
- research article
- Vol. 69 (1) , 46-56
Abstract
The single breath N2-test and spirometry were carried out on two occasions 7 years apart in 460 men, 50 and 60 years old and sampled from the general population. We analyzed the relationship between the rate of decline in FEV1 during the follow-up and the steepness of the slope of phase III at the start of the study. The results showed an association between an increased rate of decline in FEV1 during the follow-up period and a steep slope of phase III at the start of the study, allowing for age, smoking habits and FEV1 at the start of the study (p < 0.001). An increase in the slope of phase III from e.g. 1.0 to 4.0% N2/l in moderate smokers was found to predict an increase in the rate of decline in FEV1 by 50%.This publication has 14 references indexed in Scilit:
- Morphology of Peripheral Airways in Current Smokers and Ex-smokers1–3American Review of Respiratory Disease, 1983
- Rapidly Decreasing Forced Expiratory Volume in One Second or Vital Capacity and Development of Chronic Airflow Obstruction1,2American Review of Respiratory Disease, 1982
- The Influence of Smoking Habits and Body Weight on Vital Capacity and FEV1in Male Air Force Personnel: a Longitudinal and Cross-Sectional Analysis1,2American Review of Respiratory Disease, 1980
- Cigarette Smoking, Aging and Decline in Pulmonary Function: A Longitudinal StudyArchives of environmental health, 1980
- Small Airway Pathology is Related to Increased Closing Capacity and Abnormal Slope of Phase III in Excised Human Lungs1–3American Review of Respiratory Disease, 1980
- MORPHOLOGIC AND MORPHOMETRIC EFFECTS OF PROLONGED CIGARETTE-SMOKING ON THE SMALL AIRWAYSPublished by Elsevier ,1980
- The Relations between Structural Changes in Small Airways and Pulmonary-Function TestsNew England Journal of Medicine, 1978
- ABILITY OF SPIROMETRY, FLOW-VOLUME CURVES AND NITROGEN CLOSING VOLUME TEST TO DETECT SMOKERS - POPULATION STUDY1977
- EFFECT OF MODIFICATION OF SMOKING HABIT ON LUNG-FUNCTIONPublished by Elsevier ,1976
- EFFECT OF SMOKING CESSATION AND MODIFICATION ON LUNG-FUNCTIONPublished by Elsevier ,1976