Dextran protection of erythrocytes from low‐pH‐induced hemolysis
- 3 July 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 250 (2) , 293-296
- https://doi.org/10.1016/0014-5793(89)80741-0
Abstract
Low‐pH‐induced hemolysis of erythrocytes is inhibited by dextrans. The protective effect was observed with dextrans larger than 40 kDa. Electron microscopy showed dextrans of 150 kDa in a tight association with the erythrocyte membrane. These results indicate that dextrans stop the low‐pH‐induced hemolysis by interacting with the acid‐induced defects in the erythrocyte membrane [(1989) Biochim. Biophys. Acta, in press.Keywords
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